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Glossary

UDI (Unique Device Identification)

Full name: Unique Device Identification
UDI, or Unique Device Identification, is a globally unique numeric or alphanumeric code that identifies a medical device throughout its distribution and use, supporting patient safety, traceability and postmarket surveillance. A UDI consists of a Device Identifier, a mandatory, fixed portion identifying the labeler and specific device model, and a Production Identifier, a conditional, variable portion capturing information such as lot number, manufacturing date or expiration date. 

Quick facts

Category Standardized medical device identification and traceability system
Used by Medical device manufacturing and distribution
Also called UDI, DI (Device Identifier), PI (Production Identifier)
Related standards FDA 21 CFR Part 830, EU MDR, ISO 13485
Related processes Lot traceability, serial number traceability, product design controls, EU MDR
Semantic match UDI, Unique Device Identification, Device Identifier, Production Identifier, medical device traceability

What is UDI (Unique Device Identification)?

UDI provides a standardized way to identify medical devices consistently across manufacturing, distribution and use, improving traceability and supporting more effective postmarket surveillance, incident reporting and recall response.

A UDI is composed of two parts. The Device Identifier, or DI, is a mandatory, fixed portion identifying the labeler and the specific version or model of a device. The Production Identifier, or PI, is a conditional, variable portion that can include information such as batch or lot number, manufacturing date, expiration date, or a distinct identification code for certain human cell or tissue-based products.

Devices must display the UDI in both a machine-readable form, using Automatic Identification and Data Capture technology, and a human-readable plain text format, with manufacturers responsible for obtaining UDIs from an accredited issuing agency such as GS1, HIBCC, or ICCBBA for certain tissue-based products.

Why is UDI (Unique Device Identification) important?

UDI significantly improves patient safety by enabling more accurate device tracking through the supply chain, supporting faster and more precise recalls or safety corrective actions when a device issue is identified.

Consistent device identification also reduces medical errors, since healthcare providers and systems can more reliably confirm exactly which device and lot is in use for a specific patient.

For manufacturers, UDI compliance is a regulatory requirement in multiple major markets, including the United States and European Union, making it essential infrastructure for global medical device distribution.

How does UDI (Unique Device Identification) work?

A typical UDI implementation process includes:

  1. Issuing agency selection. Obtain UDIs from an FDA-accredited issuing agency such as GS1 or HIBCC.
  2. DI assignment. Assign a Device Identifier for each specific device model or version.
  3. PI assignment. Include Production Identifier information such as lot number or expiration date where applicable.
  4. Labeling. Display the UDI in both machine-readable and human-readable formats on device labels and packaging.
  5. Database submission. Submit device information to the relevant regulatory database, such as FDA's GUDID.
  6. Ongoing maintenance. Update UDI information when significant device changes occur.

Device Identifier (DI) vs. Production Identifier (PI)

Comparison Device Identifier (DI) Production Identifier (PI)
Nature Mandatory, fixed Conditional, variable
Identifies Labeler and specific device model Lot, batch, manufacturing or expiration date

Real-world examples of UDI (Unique Device Identification)

A medical device manufacturer obtains a Device Identifier from GS1 for a new product line, submitting the required information to FDA's Global Unique Device Identification Database before market launch.

A hospital scans a device's UDI during a procedure, automatically capturing the specific lot number and expiration date in the patient's electronic record for traceability.

A manufacturer issues a targeted recall using UDI data to precisely identify which distributed lots are affected, rather than recalling an entire product line broadly.

Regulations and standards related to UDI (Unique Device Identification)

The FDA established UDI requirements under 21 CFR Part 830, requiring device labelers to include a UDI on labels and packaging and submit device information to the Global Unique Device Identification Database, with a phase-in period that concluded in 2024.

EU MDR similarly requires UDI assignment for devices marketed in the European Union, and other jurisdictions, including South Korea and Singapore, have implemented their own UDI database systems generally aligned with the International Medical Device Regulators Forum framework.

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How QT9 helps with UDI (Unique Device Identification)

QT9 QMS and ERP capabilities supporting UDI compliance

  • Centralize UDI, labeling and post-market data for EU MDR and FDA technical files.
  • Support lot and serial number traceability connected to UDI data.
  • Automate labeling processes to ensure UDI compliance on device packaging.
  • Maintain device history records connecting production data to assigned UDIs.
  • Support faster, more targeted recalls using UDI-linked traceability data.
  • Integrate UDI data across design, production and distribution activities.

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Common mistakes with UDI (Unique Device Identification)

Common mistakes include failing to update UDI information when a significant device change occurs, such as a brand name change, which typically requires a new Device Identifier.

Other problems include inconsistent UDI data submission to regulatory databases, creating gaps between what is physically labeled on a device and what is recorded in systems like FDA's GUDID.

Frequently asked questions

A UDI consists of a Device Identifier, a mandatory, fixed portion identifying the labeler and device model, and a Production Identifier, a conditional, variable portion that can include lot number, manufacturing date or expiration date.
The device labeler, typically the manufacturer, is responsible for obtaining a UDI from an FDA-accredited issuing agency, such as GS1, HIBCC, or ICCBBA for certain human cell or tissue-based products.
Most medical devices require a UDI, though FDA may grant written exemptions for certain devices, and the requirement has been phased in over time with the phase-in period concluding in 2024.
In the United States, manufacturers submit device information to FDA's Global Unique Device Identification Database, known as GUDID, which is searchable by patients, healthcare providers and industry.
A Device Identifier typically needs to change when significant modifications occur, such as a brand name change or a significant change to the device itself, following rules set by the issuing agency and FDA.
Yes. EU MDR requires UDI assignment for medical devices marketed in the European Union, alongside similar requirements in other jurisdictions generally aligned with the International Medical Device Regulators Forum framework.

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Last reviewed: July 21, 2026